Based on genetic diversity in the population, there is an expectation, born out by decades of experience, that a given drug or treatment will not be equally efficacious for all patients.
The prevention of rubella normally comes as part of the MMR vaccine, which has been found to be very efficacious for all three viral illnesses [ 54].
Tamoxifen and other selective estrogen receptormodulators (SERMs) offer a new preventive strategy for some high-risk women,but have not yet been shown to be efficacious for all women.
Cochrane reviews using indirect comparisons of biologics in different patient populations (DMARD- and anti-TNF inadequate responders) support these findings, reporting similar efficacy for all biologics, with the exception of anakinra which appears less efficacious [ 24].
Effect of vaccine characteristics and transmission intensity: In low transmission settings, low or moderately efficacious blood-stage vaccines avert comparable proportions of disease episodes and deaths to those averted by PEV with comparable efficacy for all delivery modalities.
Our recent pilot study demonstrated mindfulness-based cognitive therapy (MBCT) is a potentially efficacious headache pain treatment; however, it was not universally effective for all participants.
The institute experience may prove to be an effective investment and efficacious teaching/learning strategy for all involved parties--the postdocs and graduate students, the faculty, employers, and mentors, as well as the discipline and the professional society.
Combination therapy, with a statin and a fibrate or a statin and niacin, may be efficacious for treatment for all three lipid fractions, but this combination is associated with an increased risk for abnormal transaminase levels, myositis, or rhabdomyolysis.
Combination therapy, with a statin and a fibrate or statin and niacin, may be efficacious for treatment for all three lipid fractions, but this combination is associated with an increased risk for abnormal transaminase levels, myositis, or rhabdomyolysis.
The pathogenetic heterogeneities observed among patients (see www.nPOD.jdrf.org ) might not be conducive for the development of a monotherapeutic agent that will be efficacious and safe for all diabetic patients.
Combination therapy with a statin and a fibrate or a statin and niacin may be efficacious for treatment of all three lipid fractions, but this combination is associated with an increased risk for abnormal transaminase levels, myositis, or rhabdomyolysis.
