Accordingly, it would be clinically important to know an estimate of the relative treatment efficacy or ranking of the most efficacious drugs.
Several highly efficacious drugs such as salicylate, metformin, or imatinib exhibit enhanced therapeutic efficacy through interactions with multiple targets simultaneously.
They will not be cured by our most efficacious drugs or slain with our sharpest swords.
However, many safe and efficacious drugs induce transient elevations of human liver enzymes.
The past decade, several highly efficacious drugs have been approved for the treatment of multiple myeloma.
Antibiotics are probably the safest and most efficacious drugs ever produced but they have an Achilles heel.
But such discoveries are still a long way from safe and efficacious drugs, and GSK's late-stage pipeline remains weak.
As a result of highly toxic and long-duration treatments, novel, safe and more efficacious drugs are essential.
As a result of highly toxic and long-term treatments, novel, safe and more efficacious drugs are essential.
However, in the case of pharmaceutical compounds, there may also be limitations with regard to achieving safe and efficacious drugs that are at the same time environmentally friendly.
Lithium is one of the most widely used and most efficacious drugs in the different treatment phases of bipolar disorders (Severus et al. 2012).
