Sentence examples for efficacious dose from inspiring English sources

The two chemicals have similar potency and efficacy, and the same most efficacious dose around 10 9 to 10 8 M.

Non-invasive time-course measurements may deliver apt information both on the efficacious dose as well as the dosing intervals required to maintain the targeted efficacy using a minimum of experimental animals.

Both compounds were devoid of gastric effect at the efficacious dose.

The data show that high in vitro DEI values can be associated with lower efficacious dose.

The most efficacious dose tested (30 mg of tamoxifen per kg of diet, yielding 4 6 mg of tamoxifen per kg of body weight per day) was similar to that producing optimal disease prevention in a mouse model of DMD36.

The objective of the present study was to identify the most efficacious dose of Q-Gel for use in supplementation studies.

To determine the lowest efficacious dose of oral meloxicam for relieving pain in cats with a sodium urate (SU -induced acute inflammatory SU -induced

This study thus shows that the intraorgan targeting of drugs through cell type-specific delivery holds substantial promise towards lowering the minimal efficacious dose administered systemically.

In this communication, we evaluated pharmacokinetics (PK), pharmacodynamics (PD) and sub-chronic toxicity of PEG-CBS in homocystinuric mice, wild type rats and monkeys to estimate the minimum human efficacious dose for clinical trials.

Conclusion(s): In postmenopausal women with uterine leiomyomas, it is necessary to use the minimal efficacious dose of progestin during HRT because of a higher risk to increase the tumors dimensions.

However, with this growing complexity in trial design, it becomes challenging to analytically calculate even fundamental operating characteristics of these trials, such as (i) what is the probability that the design will identify an acceptable, i.e. safe and efficacious dose level?