To understand why prophylactic treatment with both products is efficacious, we conducted a pharmacokinetic study.
With respect to FA dosage, a review of efficacious doses conducted by Wald et al. [ 112] suggested a dose-dependent effect.
Finally, more than half of the studies included in our review were conducted in international settings, and those interventions were found to be significantly more efficacious than those conducted in the U.S.
Complex interventions often prove efficacious in RCTs conducted in well-controlled circumstances, but less effective in practice [ 5, 6].
This model was used to structure the content of the therapy sessions in our Regul8 website for the MIBS pilot study, 14 which, in turn, drew from two efficacious IBS RCTs conducted by members of our research team, a nurse-delivered CBT trial 6 and a trial of a more minimal CBT based self-management programme.
According to Fischer and Ravizza, taking responsibility requires that an agent recognize that her conduct is efficacious in altering the outcome of the world around her, and she accepts that the spectrum of morally reactive attitudes of others can be properly directed at her.
In order to conduct more efficacious intervention studies in the field of health promotion, we challenge fellow researchers to perform systematic process evaluations incorporating the exploration of the key process indicators reach, dose and fidelity, as well as its association with efficacy.
Our encouraging results should prompt neighbouring endemic countries to conduct similar efficacy trials, and possibly change their anti-malaria treatment policy to this highly efficacious, safe, well tolerated and affordable ACT.
The present findings suggest that the sTMS device can be an efficacious treatment for MDD, and supports the conduct of a larger, definitive clinical trial.
In a multicentre, double-blind controlled study conducted in Sweden, PPV23 was not efficacious against overall pneumonia in middle-aged or older non-immunocompromised individuals who had been treated for community-acquired pneumonia.
