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The neutral NPs are efficacious at the proximal LN, while the fully charged NPs have no effect on either LNs.
To facilitate clinical trials of disease-modifying therapies for Alzheimer's disease, which are expected to be most efficacious at the earliest and mildest stages of the disease1,2, supportive biomarker information is necessary.
T14 and T30 were equally efficacious at the high affinity site, with maximum displacement at about 45% of total specific binding, however T30 (Ki = 16.8±1.8 pM) displayed much greater potency than T14 (Ki = 653.3±12.6 pM).
Etorphine is highly efficacious at the MOP receptor with a maximum stimulation of 115%, and is slightly less efficacious at the DOP and KOP receptors, with maximal stimulations of 60 and 98% respectively (Xu et al., 2008).
Nevertheless, the middle school students' gains were significant, indicating that the game was still efficacious at the middle school level in terms of students acquiring new science knowledge.
If we can translate this new evidence to show that this intervention is efficacious at the population level, and that this in turn prevents academic underachievement, then a potent new preventive strategy could become available to many thousands of at-risk children.
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265 268 While the GFD is efficacious at controlling the signs and symptoms of CD and improving intestinal histology in most patients, treatment of CD is currently imperfect.
We show that the treatments that spread are not necessarily those that are most efficacious at curing the ailment, and explain how 'superstitious treatments' with little efficacy and even maladaptive practices can spread under broad conditions.
Compliance with vaccines that are efficacious at reducing the incidence of severe viral respiratory infections [ 25] or the use of monoclonal antibodies to reduce the risk of RSV hospitalization in high-risk infants [ 26] may also have a significant contribution to reducing the demand of LRTIs on pediatric inpatient settings.
Use of this herd-specific multivalent vaccine designed to reduce metritis was not efficacious at reducing the risk of uterine disease or influencing production and reproduction in dairy cows.
As expected, TCDD, TCDF, and PCB126 were similarly efficacious at activating the AhR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com