At variance, anticonvulsant therapy is seldom efficacious [228].
However, there is no consensus regarding which surgical procedure is most efficacious [4, 5].
The development of levodopa is a milestone in the treatment of PD, since it is inexpensive and very efficacious [2].
Non-pharmacological pain management alternatives may also be considered; however, current data have not proven that they are efficacious [15].
A number of DNA vaccines using viral vectors have been used in prostate cancer preclinical and clinical trials and have proven safe and efficacious [67, 73 75].
15k is a potentially valuable lead compound in the development of safe and efficacious GPR40-targeted drugs to treat type 2 diabetes mellitus.
Therefore, these results suggest that ultrahigh molecular weight PolyHb solutions could be used as safe and efficacious O2 carriers for use in transfusion medicine.
A lead compound 21 was found to be a potent and efficacious GPR119 agonist across species, and possessed overall favorable pharmaceutical properties.
We have developed a series of orally efficacious IRAK4 inhibitors, based on a scaffold hopping strategy and using rational structure based design.
Jansen and Arnauld, like Bañez, defended the position that actual grace of the will is sometimes intrinsically efficacious.[27] But they disagreed about the nature of such grace.
In this regard, docetaxel (DTX), a taxane, remains an important class of antitumor agents, effective against advanced prostate cancer therapy, and until recently, only DTX-based chemotherapy is shown to be efficacious [7, 8].
