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No beneficial effects were apparent with abciximab in diabetic patients at 1 year.
The maximal level of inhibition achieved with the peptidomimetics was comparable to that of RGD-containing peptides, whereas no significant effects were apparent with an RGE-containing peptide.
Similar effects were apparent with blank targets, providing the first demonstration of crowding without a target.
Increased effects were apparent with the higher concentration of PCC after intravenous administration of dabigatran (high plasma concentration of dabigatran) and, in addition to the effects on PT, CT and CFT, clot strength (EXTEM MCF) almost returned to baseline with both doses of PCC.
Similar(56)
No such effects are apparent with MCT1.
Interestingly for cortisol we did not see such an interaction with group, only a time effect was apparent, with lower cortisol after the MR measurement.
A statistically significantly beneficial effect is apparent with recommended, higher or lower doses in all the comparisons made, except for the ACR70 response to etanercept.
Because thoracic surgery was provided in a small number of hospitals with more patients therefore having to travel further, a clear distance decay effect was apparent with the patients living in the furthest travel quartile being the least likely to undergo such treatment.
Antiproliferative effects were apparent, especially with the phosphorothioate antisense oligonucleotide, but this was independent of the p53 status of the cells (mutant, wild-type or absent) and also occurred with the control (sense and randomised) oligonucleotides.
Adherence was generally reported as high, and larger effects were apparent in trials with higher adherence (Analysis 5.8).
More definitive interaction effects were apparent for DHA, with both peak concentrations and exposure to DHA being lower in the setting of ritonavir coadministration.
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