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Side effects were analysed using the chi-squared test.
Post hoc interaction effects were analysed using the Tukey HSD test (significance level P < 0.05).
8 The influences of hospital policy towards interventions and patient clustering effects were analysed using hierarchical structures.
The long-term treatment effects were analysed using repeated measures ANOVAs with the pre-test, post-test and follow-up scores and three groups.
Individual and combination effects were analysed using an unconditional logistic regression adjusting for age, pack-years, family history of any cancer and occupation.
The Treatment, Site and Site × Treatment effects were analysed using mixed linear models (REML residual maximum likelihood) with 'block' as the random effect.
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The effect of opioid rescue medication on analgesic efficacy and the incidence of common opioid-related side-effects were analysed using meta-regression.
37 Variables measured multiple (>2) times during the supplementation period (body weight, postprandial glucose, postprandial insulin response, PYY, GLP-1, VAS, side effects assessment) were analysed using multilevel mixed effects models to account for the variability within and between subjects.
The dose-effect curves were analysed using Prism software (GraphPad Software, San Diego, CA, USA).
The anti-invasive and anti-angiogenic effects of parthenolide were analysed using in vitro invasion and angiogenesis assays.
The effects of each parameter were analysed using 3D surface plot and analysis of variance (ANOVA).
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