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A polynucleotide ligase that effects the formation of the phosphate bond between adjacent sugar molecules is concerned with the repair function but may also have a role in synthesis.
Particular focus is placed on oxaliplatin's biological mechanisms of action, including cell cycle effects, the formation of DNA adducts and interstrand cross-links and the role of DNA repair proteins.
The activation step, catalyzed by an aminoacyl tRNA synthetase specific for a particular amino acid, effects the formation of an aminoacyl AMP complex [88a] in a manner somewhat analogous to reaction [77]; ATP is required, and inorganic pyrophosphate is a product.
If its expression is not properly controlled, GluRδ2 effects the formation of excess PF contacts, which is detrimental to cerebellar circuitry.
Consistent with previous results [5], we find that Shank1b failed to enhance the density of filopodia in hippocampal neuronal cells compared to control cells, suggesting that Shank1b differentially effects the formation of filopodia compared to GAP 1 14, Cdc42 (CA -Palm and NLG-1.
In addition to its direct cytotoxic effects, the formation of new tumor colonies was markedly reduced.
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Fusion welding, brazing, and soldering always involve the application of heat to effect the formation of chemical bonds to produce a sound joint among materials.
Due to this hedge-row-effect, the formation of clustered tiny shoots causes difficulty in harvesting.
Thus, electroporation has a beneficial effect: the formation of pores prevents the development of an excessively high Vm and limits the damage to the tissue.
Next, due to the chelation effect, the formation of the metal ions-ETDA complexes reduces the free metal ion concentration [19].
Another radiation damage effect, the formation of gas bubbles known from cryo-TEM, was observed for wet-STEM as well.
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