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Despite recent studies reporting mostly additive interactions between contaminant and climate change effects, the consequences of multi-stressor exposure are still largely unknown.
This type of systems level computational modeling has the potential to assess potential off-target effects, the consequences of pharmacologically active human metabolites, the effect of comedications, and the impact of well described genotypes.
Although, in clinical studies and in clinical use so far they have not demonstrated major adverse effects, the consequences of long-term therapy with DPP-4 inhibitors (especially in susceptible patients with other chronic diseases) need to be evaluated.
First, experiments in laboratory and field settings can be used to establish which environmental factors can induce transgenerational effects, the consequences of these effects for offspring fitness and, where possible, the proximate basis of the effects.
Accumulating evidence suggests that, in addition to having local effects, the consequences of tumour hypoxia can be systemic, leading to the formation of pre-metastatic niches that can later foster metastatic colonization in distant organs.
A considerable body of evidence suggests that patients have practical problems with taking medicines or may even be reluctant to take them because of concerns about side effects, the consequences of dependency or being unclear about the benefits [ 1, 2].
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As I said before, because of the societal effect, the consequences of a pandemic now could be worse than they were in the past, despite our more advanced medicine.
Biophysical legacy effects include the consequences of past disturbances such as extreme weather events and pest and disease outbreaks.
However especially in the developing world, there is limited data available to evaluate the effects and the consequences of privatization.
This money would then go towards subsidising adaptation projects in developing countries, especially those which are or will be severely effected by the consequences of climate change.
How then is this effect, the consequence of such prodigious velocity, guarded against?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com