Sentence examples for effects severe from inspiring English sources

However, several critical defects of those traditional drugs, such as modest therapeutic effects, severe side effects and extremely high costs, necessitate the development of novel therapeutic agents.

KeySpan, which has nearly 500,000 gas customers in Nassau and Suffolk, said the drill was "an effort to prevent the effects severe weather may have on constrained oil inventories this winter" on Long Island.

So Gottschalk started taking Rebif, giving himself two shots a week until the drug's side effects — severe flulike symptoms for 24 hours — became too much to bear.

Many patients call it the "red devil" because of its terrible side effects — severe nausea, constipation, mouth sores and serious declines in white blood cells that protect against infections.

Qsymia was neither the best nor the worst of the five available weight-loss drugs in its link to adverse events — apparent side effects severe enough to prompt patients to discontinue the drug.

Adverse effects severe enough to discontinue medication were reported by 23 patients (11.3%).

As a net effect, severe plastic deformation results in softening of the binary Al Zn and Al Mg alloys.

One person in the intervention group discontinued his participation after two weeks because of perceived side-effects (severe lumbal muscle ache).

The principal psychoactive cannabinoid in cannabis is tetrahydrocannabinol (THC), and although cannabis is considered by many people as having few negative side-effects, severe cardiovascular complications were described such as myocardial infarction, sudden death, peripheral arteritis, and stroke [ 5– 7].

(The drugs have serious side effects, including severe mood alteration, weight gain, stunted growth, suppressed puberty, and increased bone fragility).

But there can be dangerous side effects, including severe immune reactions or accidental infection with other viruses.