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Because Ancova based on linear model with imbalanced data produced numerous difficulties [28], we used the most appropriate statistical tool, i.e., a mixed model with the following fixed effects: protocol factor, diving, individual factors such as age, weight, etc. and characteristics of the dive profile (e.g., duration of the dive, water temperature, etc).
In case of any adverse effects, an adverse effects protocol is followed.
Inverse Cycle Threshold values (ICT) obtained in rtPCR from each tonsil homogenate and after each one of the 9 enrichment procedures were analyzed as the quantitative dependent variable for the main experimental categorical effects: protocol, dilution and incubation temperature.
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Properly constructed mixture samples can be used to correct for systematic measurement errors, provide ongoing monitoring of performance, serve as a tool for interlaboratory comparison, and create a context for evaluating batch effects, protocols, and informatic analyses.
To avoid these serious side-effects, protocols of regional citrate administration have been developed along with the use of postfilter and systemic ionized calcium measurements.
The subsequent three-way analysis of variance (site×time×protocol) did not show a significant interaction effect or "protocol" main effect, suggesting that the two protocols share an underlying mechanism.
WASHINGTON, April 21 — The Chinese president, Hu Jintao, wound up a four-day visit to the United States on Friday with a foreign policy address at Yale that offered an upbeat vision of Chinese-American ties, as the two sides tried to shake off the lingering effects of protocol blunders during the White House reception for Mr. Hu.
The three-factorial ANOVA revealed no main effects of protocol (p>0.1) or group (p>0.3), but a main effect of time (F1.75, 37.29 = 6.62; p = 0.003) and an additional interaction between time* protocol (F6, 108 = 2.43; p = 0.03) occurred.
The three-factorial ANOVA revealed no main effects of protocol (p>0.1) or group (p>0.5), and no interaction (p>0.1), but a main effect of time (F1.75, 33.15 = 8.62; p = 0.001; Fig. 4a c).
Random effects for protocol (trial) were also considered but did not result in statistically nonzero variances and were removed before the final fitting of our models.
Subgroup analyses were performed to explore the effect of protocol deviations on the primary outcome.
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