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The major finding of this study is that the majority of the non-synonymous sequence variations in NPC1L1 identified by resequencing individuals with plasma campesterol:lathosterol levels at the extremes of the population distribution had severe adverse effects on the expressed protein.
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Carboplatin treatment had the greatest effect on the expressed genes (top three quartiles of gene expression).
However, as a note of caution, it has been reported that the expression of GAL4, which is intrinsic to our model, has a dosage and temperature dependent deleterious effect on the expressing cells [27], [28].
The presence of Aven did not have any significant effects on the luciferase expressed from pGL3 or pGL3-MLL4 G4mutant. pGL3-MLL4 G4mutant
We conclude that estrogen mediates greater host resistance to pneumonia in female mice via effects on the constitutively expressed NOS3 in lung macrophages.
The first is to compare a number of between-array normalization methods by analysis of their effects on the differentially expressed genes deduced from an exemplary data set for which we have some background knowledge.
The specific effect of AT1001 on the expressed mutant form of α-Gal A was determined by subtraction of the endogenous HEK-293 cell wild-type α-Gal A activity as a function of AT1001 concentration.
Coinfections had various effects on the population expressing GFPVP2.
After 36 h, insulin release was similar to that of the control cells most likely because of the 'dilution effect' caused by cell proliferation on the expressed transgene that was delivered with an adenoviral vector.
A generalised model of a mono-articular muscle tendon complex was used to examine the effect of various muscle architecture parameters on the expressed section of the force length relationship for a 90° joint range of motion.
To circumvent the effect of HLA and other loci on the expressed TCR repertoire, we compared the TCR repertoire in nine pairs of monozygotic twins who were discordant for HIV infection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com