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Furthermore, three classes of pharmaceutical drugs had similar effects on the engineered muscle as they do on normal muscle tissue in clinical settings.
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Finally, the effect of the engineered particles on vitality of human airway epithelial cells of patients homozygous for ΔF 508 CF (CuFi1) was studied and compared to that of raw active compound.
The effect of the engineered STAT1 constructs on the production of full length infectious HCV were examined by a multicycle infectivity assay as previously described [22].
Thus, the two mutations had no significant effect on the engineered enzyme's thermal stability (p = 0.45).
The observed stimulatory effect of CO2 on the engineered strains will not hinder application of this concept in industrial bioethanol production, since large-scale processes for bioethanol production are characteristically CO2 saturated.
The overexpression of GDNF, regardless of the promoter employed, had no obvious adverse effects on astroglia and the engineered cells stably produced and secreted GDNF for extended periods of time (≥ 3 weeks).
Also, we estimated the effect of each design variable on the sealing effect and presented the engineered value of design variables, not experienced ones.
Findings from this study confirm that the polymerization mechanism and network structure have long-term effects on the quality of engineered cartilage, especially under mechanical loading.
It is then clear that in scaffold architecture the level of heterogeneity rather than self-similarity could have marked side effects on the quality of the engineered tissue, eventually giving also rise to scale effects.
Chloride is of concern because elevated concentrations can have adverse effects on engineered and natural systems.
This had an effect on the ASR amounts between the engineered lines, which could be important for pretreatment and sugar recovery.
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