Nevertheless, this study is one of the few randomized studies studying EPO effects on renal function and is the only one testing the effect of EPO on inflammatory markers such as cytokines.
An often cited concern with HP diets is the potential adverse effects on renal function and bone health.
Overall, the data suggest similar effects on renal function among all NSAIDs when used at comparable doses.
Previous studies suggest that adenosine A₁ receptor antagonists may promote natriuresis without deleterious effects on renal function.
Furthermore, effects on renal function were investigated using plasma clearance of iohexol.
Also, the administration of a starch solution could have produced deleterious effects on renal function [30].
Others have shown negative impacts: for example, in a prospective cohort study, hyperoncotic albumin infusion was associated with harmful effects on renal function and outcome [3].
Our findings support this, with no evidence of adverse effects on renal function or cardiac perfusion, and no evidence of excess in-hospital mortality or post-discharge recidivism.
Other reports of long-term lithium treatment effects on renal function are consistent with this observation (Bendz et al. 2010; Bocchetta et al. 2015; Shine et al. 2015).
However, treatment with exogenous NO in experimental renal IRI has resulted in contrasting results including beneficial, detrimental, or no effects on renal function [11 15].
There is no study regarding the use of tranexamic acid in a curative intent and its possible adverse effects on renal function.
