Exact(14)
Mature retinal ganglion cells (RGCs) cannot regenerate injured axons because some neurite growth inhibitors, including the C-terminal of Nogo-A (Nogo66), myelin-associated glycoprotein (MAG) and Omgp, exert their effects on neuron regeneration through the Nogo receptor (NgR).
To characterize thrombin's effects on neuron survival, we spectrophotometrically measured changes in enzymatic activity.
Dopamine effects on neuron excitability had been widely shown.
Therefore, we next asked whether TIMP-1 also elicits autocrine effects on neuron outgrowth.
A varying driving force of the synaptic current resulted in relevant effects on neuron excitability.
Other roles of leptin within the brain include effects on neuron excitability and on synaptic plasticity [16] [18].
Similar(46)
Opioids produce effects on neurons by interacting with receptors located on neuronal cell membranes.
These deleterious effects on neurons are apparently buffered by activation of neuronal repair mechanisms, one of which involves neuronal expression of vimentin.
It is mostly expressed by glial cells and in neuronal subpopulations [ 7, 8] and exerts paracrine and autocrine effects on neurons and glia.
Accordingly, whether GR could be effectively distributed into brain tissue and directly carry out potent neuro-protective effects on neurons remains unclear.
Some experts think some anticancer drugs could have direct toxic effects on neurons, although most drugs do not penetrate the blood-brain barrier.
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