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Importantly, many of the anti-diabetic drugs currently in clinical use, though effectively treating symptoms, have limited effects on disease progression.
No cures for ALS exist and approved therapies have marginal effects on disease progression and survival.
We also found that network variables had interactive effects on disease spread.
All those treatments show additional beneficial effects on disease progression.
With huge numbers of people in these studies, scientists can search for genetic variations that have subtler effects on disease.
This method provides a tool for gauging the extent of environmental effects on disease emergence.
Yu H, Choo S, Park J, Jung J, Kang Y, Lee D. Prediction of drugs having opposite effects on disease genes in a directed network.
While network variables had interactive effects on disease spread, their relative importance was generally smaller compared with main effects of network variables.
Moreover, both connectance and diversity had indirect effects on disease spread via nestedness (connectance increased and diversity decreased), which directly constrained disease spread (Fig. 4c).
The children were subsequently evaluated for engraftment, adverse effects, and effects on disease symptoms.
Their detailed effects on disease resistance were recently reviewed (Pandey and Somssich 2009).
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