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Reduction of PDGF-BB was effective in preventing vasospasms, and direct vasoconstrictive effects on cerebral arteries were shown in rabbits [ 40].
Minocycline, an antibiotic that effectively crosses the blood brain barrier, has been found to have significant neuroprotective effects on cerebral ischemia disorders, 20, 21 demyelinating diseases, 22, 23 and especially in neurodegenerative disorders including amyotrophic lateral sclerosis, 24, 25 AD, 26 Huntington's disease, 27, 28 and Parkinson's disease.
Vestibular effects on cerebral blood flow.
Several studies have evaluated the effects on cerebral activation of the common val158met polymorphism.
It is well established that insulin-like growth factor (IGF -1 has potent neuroprotectIGF -1fects on cerebral ischasia in the rat and sheepotentl.
Water electrolysis-derived hydrogen inhalation had neuroprotective effects on cerebral ischemia/reperfusion injury in rats with the effect of suppressing oxidative stress and inflammation, and it is a possible new hydrogen resource to electrolyze water at the bedside clinically.
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Furthermore, flunarizine has proven to be effective in preventing ischemia in subarachnoid hemmorrhage, although its effect on cerebral infarction has not been proven yet [49].
Towards evaluating the therapeutic potential of tDCS in acute stroke, we investigated tDCS-effects on cerebral blood flow (CBF) in a tDCS rat model adapted for this purpose.
However, its effect on cerebral circulation in ischemic conditions is not yet fully elucidated.
It has been reported that it may have a potential effect on cerebral injury.
Sequential hormone replacement therapy exhibits an overall neutral effect on cerebral blood flow.
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