Sentence examples for effects of these variant from inspiring English sources
Table 1 shows that the effects of these variant RNA sequences (shown in Figure S2) are negligible: all of the hairpin RNAs have affinities for JAZ ZF34 similar to that of T57A RNA (C50 ≈ 60 80 nM).
This review will focus on the most common and widely studied SNPs of oxidative DNA damage repair proteins trying to bridge the information available on biochemical and structural features of the repair proteins with the functional effects of these variants and their potential impact on the pathogenesis of disease.
"The effects of these variants didn't just add together in a simple way," says Burn. "There were some situations where a variant was a disadvantage unless it was in the presence of another variant when it became an advantage.
We aimed to replicate this finding in an independent cohort from the Study of Viral Resistance to Antiviral Therapy of Chronic Hepatitis C and to investigate the effects of these variants beyond week 4. METHODS:Genetic material was available from 318 patients.
These consistent findings from three independent cohorts strongly support the risk effects of these variants on GSIS to predispose hyperglycemia in Chinese.
Thus the effects of these variants on clinical characteristics in the Chinese still need to be investigated in cohorts with more samples.
To investigate the effects of GCK, GCKR, G6PC2 and MTNR1B variants on biphasic insulin secretion, we tested the individual as well as combined effects of these variants on the traits related to glucose metabolism, especially multiple measurements on insulin secretion.
Given the fact that these are novel variants, we ran the analysis software SIFT (available at http://blocks.fhcrc.org/sift/) [26] in order to have some insight into the potential effects of these variants.
24 common variants associated with adult adiposity did not affect or interact with birth weight among Danes suggesting that the effects of these variants predominantly arise in the post-natal life.
However, Heni et al showed the impact of genetic variation on insulin secretion depends on glycaemia [25], [26], what are the effects of these variants in the diabetic patients and prediabetes subjects remained unknown and to be investigated.
