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The effects of the formulation variables on pellet properties were evaluated by analysis of variance.
Experimental designs in combination with multivariate data analysis were applied to reveal the effects of the formulation variables on the responses.
A Design of Experiment (DoE) was employed for the screening of the effects of the formulation variables related to the presence of unloaded microparticle (MPs) on the cement most important mechanical properties.
The response surfaces estimated by RSM-S visualized the effects of the formulation factors, and the optimal release profile for diltiazem was predicted quantitatively as a function of the quantities of the formulation factors, using RSM-S.
The effects of the formulation on lycopene encapsulation, stability, and release were analyzed, as well as the physicochemical properties of the obtained systems.
The skin of the leg in Fig. 2 also shows that the atopic dermatitis symptoms were relived; thus, the effects of the formulation used in the clinical trial could be identified.
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Extrapyramidal side effects of the formulations were also studied.
To measure the effects of the formulations on endogenous P. aeruginosa, aliquots of sputum samples were also stored at 4°C and used within 24 h of collection.
The effect of the formulation of these parameters on the perturbed velocity field has been investigated in detail.
Such reduction occurred in lower extent in the nanoemulsions, suggesting a protective effect of the formulation to β-caryophyllene content.
In conclusion, this investigation demonstrated the potential of QBD in understanding the effect of the formulation variables on the quality of CyA self-nanoemulsified formulations.
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