Sentence examples for effects of such mutations from inspiring English sources

However, unintended effects of such mutations have already been evaluated and excluded during the safety assessment of the GM (single).

ISRIB induces dimerization and complex stability and thus may rescue the effects of such mutations.

We have already published a study of the effects of such mutations to nonpolar residues in α-helices.

At the same time, animal models can be used to investigate the effects of such mutations on tissue development and morphogenesis.

Studying the effects of such mutations on channel function and relating these changes to clinical manifestations offers ample opportunities to study 'human biology'.

Additionally, animal models in which genes of the ERQC pathway are disrupted have proven invaluable in understanding the effects of such mutations at the physiological level.

The mutator effect of such mutations is unexpected, since in classical studies with T4 DNA polymerase, mutants that lead to increased nucleotide turnover were antimutators (see [ 33]).

P2) There is no unintended effect of such mutations in the parental GM (single).

Selection of I54T and Q58E mutations during darunavir therapy may be explained due to residual phenotypic or compensatory effect of such mutations on darunavir susceptibility, genome colinearity with other darunavir-associated mutations, or simple stochastic effects.

Currently it is unclear whether the lack of homozygous missense mutations is a chance observation or possibly reflects a distinct functional effect of such mutations, leading to a different phenotype.

Therefore, long-term efficacy data of raltegravir used in combination with other active antiretrovirals is required to evaluate the effect of such mutations on overall viral infectivity and to understand their impact on raltegravir efficacy.