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The changes are reflected by significant effects of stage on proportions of LL, RR and LR (Table 1).
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Effects of stages of change on outpatients and non-chronic patients might be different.
There was a small effect of stage of lactation on induction time, with an increase of about six seconds (12.2 %) at the end of lactation.
Moreover, the presence of hormone therapy reduced the effect of stage on the risk of death from breast cancer (HR of interaction term: 1.08).
To control for the effect of stage on phenotypes, we first assigned patient samples to early (<15 hours) versus late (≥15 hours) stage groups.
We allowed the effect of stage on survival to vary for men and women by including an interaction term between stage and sex in the model.
Since the modernisation of the English cancer registry, the recording of stage has been much improved and we will be able to analyse the mediation effect of stage on survival when the 2012 data has accrued a few more years of follow-up for death.
This is in accordance with some (Auvinen, 1992; Byers et al, 2008; Yu, 2009; Sprague et al, 2011) but not all (Hole and McArdle, 2002; Frederiksen et al, 2009) studies investigating the effect of stage on social disparities in survival from cancers.
Evaluating cows during the early postpartum period will provide additional information on the effect of stage of lactation and nutrient supplementation on PMN function.
These results also only give a crude assessment of the possible effects of stage, early diagnosis and treatment on outcomes.
The zebrafish presents an exceptional opportunity to explore the potential synergistic effects of developmental stage on dietary lipid regulation of apolipoprotein transcription.
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