Sentence examples for effects of small molecule from inspiring English sources

Targeting PI3Ks have produced therapeutic effects of small molecule inhibitors.

These nanocarriers can also reduce the undesirable adverse effects of small molecule therapeutic agents.

Here we investigated the effects of small molecule inhibitors (SMIs) designed to disrupt integrin α2 I or β1 I-like domain function on angiogenesis.

Thus, the FRET-based Atg4 assay can quantitatively determine the effects of small molecule modulators of Atg4A and Atg4B.

In contrast to the effects of small molecule allosteric regulators, the substrate-binding pocket is intact in the mutant, yet the enzyme is inactive.

From the therapeutic point of view, the off-target effects of genetically engineered nucleases are tantamount to the side and toxic effects of small molecule drugs.

The analysis of the biological effects of small molecules by mining lot of growing databases is an important task in the field of pharmaceutical sciences.

These populations are typically assembled using cancerous cell lines that already have altered morphology together with genomic mutations capable of masking effects of small molecules.

In the scientific literature, there is a tremendous amount of information about the interaction of small molecules with specific targets, the influence of small molecules on biochemical pathways, the phenotypic effects of small molecules in different cell types, as well as the relationship of small molecules, targets, pathways and phenotypes to disease processes.

Due to the concentration-dependent effects of small molecules on their targets, it is also possible to uncover phenotypes that result from partial inactivation of a pathway.

First, a large library of perturbations is needed in order to filter non-specific effects of small molecules.