Sentence examples for effects of radionuclide from inspiring English sources

These findings expand the knowledge base on normal tissue responses and may help to evaluate and limit side effects of radionuclide therapy.

However, the extensive experimental and clinical knowledge on the effects of external radiotherapy can be deployed to only a limited extent in understanding the effects of radionuclide therapy.

This life history is advantageous for monitoring the biological effects of radionuclide contamination because the radioactive fallout accumulates on the ground.

Nevertheless, up to now very little consideration has been given to the effects of radionuclide therapy at the cellular and molecular level [ 106].

As a preliminary approach to understand the combined effects of radionuclides, exposure studies were designed using gamma radiation (Gamma) and depleted uranium (DU) as stressors, representing a combination of radiological (radiation) and chemical (metal) exposure.

In this review, we describe our efforts to create a form of gene-targeted radiation therapy by using the unique radiation effects of radionuclides that decay by the Auger process attached to oligonucleotide carrier-molecules that are capable of forming triplex DNA structures with target sequences in the genome of the human cancer cell.

In the present work, plasmid DNA was used as a valuable tool to understand the radiation effects of radionuclides with different LET.

We have experimentally compared toxic effects of radionuclides in thyroid follicle cells and shown that the highest effect was obtained for 211At, followed by 123I (emits Auger and conversion electrons similar to 125I), while the least effect was obtained by 131I [44].

Despite modest human epidemiological evidence of uranium nephrotoxicity and radium bone carcinogenicity, available studies do not clearly demonstrate the health effects of radionuclides at levels naturally encountered in drinking water.

As far as research needs go, a commentary in the December 2011 issue of EHP points to some of the work needed to gain a better understanding of health effects of radionuclides at exposures typically encountered in drinking water.

Indeed, the existing epidemiological studies do not allow clearly demonstrating health effects of radionuclides at levels naturally encountered in drinking water due to methodological limitations (exposure assessment, possible confounders, and limited sample size).