Sentence examples for effects of pathway from inspiring English sources

The potential link between DISC1, huntingtin and their interacting partners may open new areas of research into the effects of pathway dysregulation in severe neurological disorders.

A mechanistic understanding of the effects of pathway perturbation is required to accurately relate chemical impacts across species.

The MET inhibitor PHA-665752 was used to study effects of pathway inhibition in basal and hepatocyte growth factor (HGF -stimulated conditions.

In hierarchical screening, common in the pharmaceutical industry, simple cell-line-based assays are used as a preliminary screen for interesting effects of pathway modulators.

However, activation of WNT signaling below the level of ligand function or cytoplasmic transduction, as in the case of loss of APC for instance (see above), would appear to complicate the effects of pathway blockade at upstream levels.

In this study, we aimed to confirm the link between WNT/ β-catenin pathway activation and prognosis in supratentorially located CNS PNET and additionally investigate the biological effects of pathway activation.

Using data on New York City students and their teachers in grades three through eight, we assess the effects of pathways into teaching on the teacher workforce and student achievement.

We further only touched on the effects of pathways and intermediate states because experimental data are scant.

Such designs are likely to be misleading and contribute little to understanding the reported effects of pathways.

This raises the question of possible downstream effects of pathways that may contribute to a more invasive and motile behavior of tumor cells.

Furthermore, the effect of pathway perturbation may depend upon the precise cell type, with potentially differential effects occurring in epithelial and stromal cells.