Also, spousal stress has been associated with strokes in the left hemisphere, suggesting the effects of impairments in communicative competence [ 37].
Dizziness in older persons has, due to its complexity, been described as a geriatric syndrome [ 4, 9], a multifactorial health condition that occurs when the accumulated effects of impairments in multiple systems render a person vulnerable to situational changes [ 9].
We used multiple linear regressions to develop a model for the effect of impairment on wellbeing, carrying out tests of the effect of impairment after adding in potential confounding variables.
A recent review concluded that much of the effect of impairment on negative affect could be explained by the potential mediating effect of disability [ 30].
Independent of age and gender, there was highly significant evidence of a graded effect of impairment on participation (t = 14.277 p < 0.001).
Geriatric syndromes are multifactorial health conditions that occur when the accumulated effect of impairments in multiple systems renders a person vulnerable to situational challenges [ 5].
Because of this, two different tests were used in this study, one to assess the effect of impairments in lower extremity functional strength and range of motion, and one to assess walking speed.
Fourth, we did not consider the effects of renal impairment; future studies should examine the impact of renal impairment on the efficacy and safety of tofogliflozin.
Relatively few of our patients were cognitively impaired, thus limiting our statistical power to determine the effects of cognitive impairment on preference measurements.
To date, only one published clinical study has examined the effects of microcirculatory impairment on end-organ function following THS [9], finding that there was an association between microcirculatory impairment and organ failure.
