Sentence examples for effects of genetic modulation from inspiring English sources

In one study, SG-1002 was administered to C57BL/6J or CSE knockout mice to investigate the effects of genetic modulation of CSE and exogenous H2S in a pressure overload-induced heart failure model.

Here we study the effects of the genetic modulation of genes encoding the components of the glyoxalase system in the filamentous ascomycete and aging model Podospora anserina.

To test this hypothesis we have investigated the effects of genetic and chemical modulation of Shh signalling on disc1 expression in the zebrafish embryo and used double-labelling methods to characterise disc1-expressing cells in the hindbrain.

Continued exploration of the combination of genetic and clinical data with highly sensitive biochemical, cell-biological and animal model systems may provide further insight into the effects of pharmacological and genetic modulation of GKRP (25– 25).

Effects of genetic drift are most pronounced in small populations.

Moreover, the contribution of host stroma-derived VEGF on the growth of different tumours may be a confounding factor in the interpretation of the effects of various pharmacological blockers or genetic modulation of tumour VEGF expression.

Among these considerations are the mechanism of tumorigenesis, timing of environmental exposure, and genetic modulation of exposure.

Going through our data, we also noticed that the effect of genetic inhibition of SIRT1 on angiogenesis response of hMSCs was less pronounced than pharmacological modulation of SIRT1.

Genetic modulation of the abundance of PaCATB identified differential effects on the phenotype of the corresponding strains.

The genetic modulation of substrate utilization similarly exhibit divergent effects.

Since the AGE-induced effects on SIRT1 and NF-κB were blocked in THP-1 cells by genetic modulation of AGER1 expression, AGER1 is likely to be involved in the regulation of inflammatory responses controlled by SIRT1.