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Theory also suggests that effects of genetic changes in secondary metabolites may depend on resource availability, so nitrogen, a main constituent of glucosinolates and myrosinase was added in fertilizer treatments to assess costs.
Chloroplasts typically have uniparental inheritance, which simplifies the interpretation of the effects of genetic changes on divergence.
Estimating kinetic parameters can be useful for identifying the effects of genetic changes or drug treatments that target metabolic enzymes.
It is indispensable to thoroughly characterize each animal model in order to distinguish between primary and secondary effects of genetic changes.
Prior to subjecting knockout mice to disease models, it is important to first assess the phenotype of these animals in order to distinguish between the primary and secondary effects of genetic changes.
The genome-scale model allows one to analyze the cell from a systems viewpoint to predict whole-cell effects of genetic changes, and to simulate known and hypothesized phenotypes.
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Study of the effects of genetic change over time revealed a pattern affected by a cataclysmic event across the species' entire geographic area about 13,000 years ago.
Considering the effects of mutations in all nonessential genes shows that genes that confer robustness to environmental or stochastic change also buffer the effects of genetic change, and with similar efficacy.
First, it is phenotypes, shaped by the joint effects of genetic change and plasticity, which interact with the biotic and abiotic environment.
The effect of genetic changes such as gene deletion can be simulated by constraining reactions associated to gene of interest to be zero [ 45].
Collectively, these models provide cell lines that represent all of the sequential stages of progression in breast disease, which can be modified to test the effect of genetic changes.
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