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Similar to the effects of compromising mutations in the SLIDE domain of ISW2 on repositioning efficiency and directionality of nucleosome translocation, the ATP binding and hydrolysis cycle of ISWI may contribute to the random walk behavior that we observe.
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"We are disappointed -- it has the effect of compromising our database," he said, adding that Lexis-Nexis expected the loss to be minor among its three billion documents from 30,000 sources.
Nevertheless, he wrote, "the music has the effect of compromising one of the crucial ambitions of the film: to refract the recent history of black America (and, by implication, America itself) through the prism of popular culture".
However, by mobilizing stem cells to leave the niche the drugs could also have the undesirable effect of compromising epithelial homeostasis in healthy tissues.
Thus, VL12.3 binding would be expected to interfere with cleavage at AA 15 and possibly sterically hinder cleavage at AA 8. To determine the effect of compromising cleavage at AA 15 on mHDx-1 clearance, we performed a TR-FRET assay to measure soluble mHDx-1 levels in lysates of organotypic brain slice cultures biolistically transfected with mHDx-1 alone or with either VL12.3 or CVL, a control iAb.
Figure 6 shows the effect of compromising Pol III complex assembly at the ZOD1 locus.
Further, the incidences of gossiping may also have the effect of compromising patient confidentiality and could interfere with the doctor-patient relationship.
(Private, expatriate) Most of the public sector participants criticized the private practitioners for being influenced by the pursuit of financial gain in their practices, which could have the effect of compromising medical care in this sector.
Typically, these so-called "man-in-the-middle" attacks install colourfully named Trojans (pieces of malware, essentially) such as Zeus, SpyEye or Citadel on computers, which have the effect of compromising, for example, online banking transactions.
Mr Kibaki has, so far, shown little sign of compromising.
He accused the government of compromising the agency's independence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com