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Until then, removing the effects of alignments from peptides in this category has the huge advantage of improving the quantitative accuracy of measuring functions in the "known" universe, and that alone is cause for implementation.
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We believe that the use of externally verified alignment scores is a far less biased and more precise metric of aligner accuracy because it isolates the effects of alignment heuristics from the mapping quality heuristics.
To understand the effects of alignment error on the different approaches, we re-aligned the reference sequences using MAFFT and PAGAN.
Effects of alignment were not consistent with existing theories, with right-aligned graphics being preferred.
Most importantly for me, are the negative effects of alignment on innovation in the sector as a whole.
Inhibition of ERK1/2 blocked effects of alignment.
We selected four sample types to investigate effects of alignment, purity, and single- or multi-wall character on their thermal conductivity.
As previously suggested, our results underscore the importance for careful exploration of the sensitivity to the effects of alignment methods for data comprising widely divergent sequences.
The effects of alignment size bias are especially noticeable for alignments containing fewer than about 100 sequences, and must be accounted for when making direct comparisons between sequence alignments of different sizes.
Procrustes superimposition was used to remove the effects of alignment, rotation or scale.
To assess the effect of alignment error in the RA, the sequences were re-aligned with PAGAN and MAFFT (Katoh et al., 2002).
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