Due to the lack of any specific parameters, we in this study decided to investigate the effect of a rigorous gDNA elimination step, i.e. DNase I treatment, on the final transcript numbers detected.
She writes that although "there has not been a conclusive study of the negative effects of … a rigorous one-size-fits-all, shoot-'em-up [vaccine] schedule, there is increasing anecdotal evidence [that some children were] 'never the same' after receiving a vaccine.
While there has not been a conclusive study of the negative effects of such a rigorous one-size-fits-all, shoot-'em-up schedule, there is increasing anecdotal evidence from doctors who have gotten distressed phone calls from parents claiming their child was "never the same" after receiving a vaccine.
Although the enduring effects of embedding a rigorous research program are not yet fully known, preliminary data suggest that these experiences instill an appreciation for research, impart research rigor and methodologies, and may motivate students to pursue careers in academic medicine.
The main advantage of the Wiener Chaos approach is that it allows for the separation of random and deterministic effects in a rigorous and effective manner.
Nonetheless, still feeling the effects of some rigorous training and a recent excursion to South Africa, Heyns is concerned.
Because of the possibility of concomitant secular trends and the effects of a changing medical environment, further rigorous research on the efficacy of individual pathways is needed.
These models need to account for the heterozygous expression of PSEN mutants in the presence of one WT allele in FAD patients, and they should allow a rigorous comparison of the effects of a larger panel of mutations in a controlled system.
The scientific contribution of the Cuban strategy could support a paradigm shift from individual protection to a population effect based on a rigorous body of scientific evidence.
There is a lack of clinical research assessing the effects of fucus and rigorous randomised controlled trials are required.
