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He has been bothered by the effects of a concussion and a car accident.
Midfield stalwart Pablo Mastroeni may also miss out because of the lingering effects of a concussion.
Will Peterson, the Giants' other starting cornerback, continues to be bothered by the effects of a concussion sustained Nov. 24.
He has played 16 consecutive games in place of Richter, who is still feeling the effects of a concussion.
Not only is Horn hurt and unlikely to play Saturday, but Poole is still feeling the effects of a concussion.
Philadelphia Eagles quarterback Michael Vick will miss Sunday's game against the Washington Redskins because of the effects of a concussion.
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Warner, playing despite the after-effects of a concussion, completed 24 of 40 passes for 365 yards with 3 touchdowns and 3 interceptions.
Swayne, who just a few months ago scored 43 touchdowns for the New York Dragons in the Arena League, will get his chance because Wayne Chrebet is suffering the after-effects of a concussion.
"I saw the same video you saw, and I'm wondering about a word called 'aphasia,' where you're searching for words, you suddenly lose those words, and that can be the sign, again, of some kind of traumatic brain injury or the after-effects of a concussion," Fox News medical correspondent Marc Siegel said.
Her opponents have also raised questions about the effect of a concussion she sustained in 2012.
She skipped the latter half of the world championships in Germany last month, suffering the effects of a mild concussion after banging her head on the snow during a fall in early February.
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