Exact(17)
We discuss three mechanical effects initiated by cosmic rays which may limit the sensitivity of gravitational wave antennas.
The main aims for the addition of PCL was to increase impact strength resistance, improve surface catalytic properties and reduce the temperature of extrusion, thus limiting degradation effects initiated by copper acetylacetonate.
Moreover, exogenous CGRP relaxed ET-1-induced contractions (Fig. 2C), prevented recovery of contractions initiated by ET-1 (Fig. 2D) and caused long-lasting inhibition of the persistent effects initiated by ET-1 (Fig. 3A/B).
Whether these Lim3 functions are sufficient to explain the lifespan variations caused by alterations in Lim3 expression in embryos, and other mechanisms that might explain lifespan effects initiated during early development are unknown.
However, much more dramatic are direct effects initiated by nutrition of pregnant animals reducing the number of live-born pups, and by the nutrition of dams during lactation significantly increasing the mortality of sucklings.
The novel finding of our work is that while ET-receptor antagonists partly and transiently reduce endothelinergic vasoconstriction as a result of bitopic and irreversible agonist-receptor binding, stimuli of SMN can terminate effects initiated by ET-1 through CGRP-receptors that promote dissociation of ET-1/ETA-receptor complexes.
Similar(43)
The work of Turqueti-Neves et al. however shows that extrafollicular IL-4, apart from its known immediate effects inducing B-cell class switch recombination, also has important downstream effects initiating the differentiation of B cells toward the follicular GC pathway.
In these earlier publications, the authors firmly condemned the use of muscle relaxants (devoid of sedative or analgesic effect) initiated just before withdrawal of mechanical ventilation with the sole aim of suppressing impending terminal signs, so as to give the appearance of a calm and serene patient.
Then again, it could be a person on the other side of the planet who is affected via the ripple effect initiated by you when you post that special picture or story on Facebook that opens hearts and puts a smile on everyone's face which they then "share" with others, and so on it goes... So, the question we must ask ourselves isn't, will I make a difference in the world?
However, these relaxations were transient and did not inhibit the persistent contractile effect initiated by ET-1.
This approach is a continuation of classical models explaining the relationship between drug concentration and pharmacological effect initiated by Clark's occupancy theory, followed by Arien's concept of intrinsic activity, and Black and Leff's theory of operational agonism that has been applied in temporal pharmacokinetic and pharmacodynamic models.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com