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Although the 6C rise and its potential disastrous effects have been speculated upon before, this is the first time that scientists have said that society is now on a path to meet it.
These effects have been speculated to occur by means of activation of D2R subfamily, especially the D3 receptor subtype, in the mesolimbic dopamine system [1].
The purpose of this study was to determine the binding sites of pramipexole in extrastriatal dopaminergic regions because its antidepressive effects have been speculated to occur by activating the dopamine D2 receptor subfamily in extrastriatal areas.
Also flavonoids, that accumulate on wounded and damaged stigmas and have anti-microbial effects, have been speculated to have a function in pathogen resistance (Stephenson 2012).
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Although several rationales have been speculated, the precise mechanism behind diabetic cardiomyopathy remains elusive.
Because the acidosis caused by the increased PaCO2 may be the main reason for the side effects of "permissive hypercapnia," it has been speculated whether treatment with sodium bicarbonate (NaHCO3) would be useful [ 1, 17, 18].
How Levetiracetam exerts its effect is not understood; it has been speculated that it may do so through the following causal chain: suppression of aberrant network activity, reversal of hippocampal remodeling, and recovery of synaptic and cognitive functions.
3, 4 Resveratrol, a phytoalexin found in grapes, mimics the effect of caloric restriction, which has been speculated to be mediated through activation of SIRT1.
An earlier study suggested that resveratrol, a phytoalexin found in grapes, mimics the effect of caloric restriction, which has been speculated to be mediated through activation of SIRT1 [ 16].
Since most studies that recruited athletes have failed to demonstrate an ergogenic effect of β-alanine, it has been speculated that this may be due to the already increased buffering capacity in highly trained individuals, limiting the measurable effect of increased carnosine content through β-alanine supplementation (Bellinger et al. 2012; Bellinger 2014).
Because of their effects in improving surrogate markers, it had been speculated that agents that reduce insulin resistance might have better outcomes than agents that provide insulin.
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CEO of Professional Science Editing for Scientists @ prosciediting.com