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In a new memoir, she confronts the drug's risks and taboos including the psychotropic effects explored by famed opium eater Thomas de Quincey.
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Dose response effects are explored by curve fitting of nonlinear models that especially have been developed to detect hormetic effects that are characterized by stimulation at lower followed by inhibition at higher dosages (U- and inverse U-shaped effects).
Non-linear effects were explored by categorizing the data.
However, some long-term effects were explored by comparing this group with the retrospective sample.
The influence of potential sources of heterogeneity on treatment effects was explored by subgroup analysis.
Associations between AUC (or clearance) and response or incidence of side effects were explored by logistic regression analysis.
The influences of a particular study on the summary effects were explored by calculating the combined HRs after randomly removing one included study.
Therefore, the second stage effects were explored by analyzing all pair wise interactions among candidate stable predictors selected in the first stage.
In case of a significant group effect between ε4 carriers and non-carriers, the dose effect was explored by comparing the results in ε4 homozygotes and ε4 heterozygotes.
Moderators of effect were explored by meta-regression.
This effect was explored by considering lesion groups separately, using similar ANOVAs but with only two groups at a time.
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