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Overall, the combined delivery of FGF-2 and VEGF resulted in superior pro-angiogenic effects (cell survival, proliferation, differentiation, and migration in vitro and CAM vascularization in vivo) relative to single factor delivery.
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Apart from effects on cell survival effects on DNA were also investigated.
See [69] for negative effects on cell proliferation and [4] for positive effects on cell survival.
Investigating the effect of IRE1 polymerization status on JNK and BAX/BAK activity may shed additional insight into IRE1's effects on cell survival.
Using this approach, researchers can turn off thousands of different genes, one per tumor cell, and then measure the effects on cell survival.
MIT biological engineers have now devised a new toxicity test that can measure chemical effects on cell survival with much greater sensitivity than some of the most popular tests used today.
This review evaluates the recent literature on the non-enzymatic, signal transduction roles of surface-bound gelatinases and their subsequent effects on cell survival, migration and angiogenesis.
During ischemic injury, activated AMPK suppressed mammalian target of rapamycin (mTOR) by phosphorylation, thereby up-regulate autophagy, to play a protective effects on cell survival during ischemia (Takagi et al., 2007).
MAPK signaling pathways have been shown to exert diverse effects on cell survival and death [70].
These antibodies could neutralize Tβ4 and prevent any beneficial effects on cell survival and decreased fibrosis.
This function may be responsible for eIF5A-mediated effects on cell survival [7], [8], [32].
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