Sentence examples for effects cardiac from inspiring English sources

Previous studies on pharmacological treatment of HCD have demonstrated beneficial effects when using drugs with the combined effects; cardiac inotropic support and peripheral vasodilation.

Despite controversy over their use and the potential for toxic side effects, cardiac glycosides have remained an important clinical component for the treatment for congestive heart failure (CHF) and supraventricular arrhythmias since the effects of Digitalis purpurea were first described in 1785.

Further, clinical developments of CXR4 antagonists have been delayed in preclinical and clinical studies due to serious side effects (cardiac abnormalities and liver toxicity) or lack of drug efficacy.

The overall early (0 2 h) and late (2 24 h) incidences of nausea, vomiting, rescue anti-emetic administration, pain, and adverse effects (cardiac arrhythmias and extrapyramidal effects) were assessed postoperatively.

The major side effects cardiac arrhythmias and cardio-respiratory collapse, which occasionally occur upon application; these potentially fatal complications are caused either by embolism from marrow contents forced into the circulation or by a direct toxic effect of the cement.

For each patient, iPSCs would be generated, expanded and (re differentiated to the type of cells most affected in the disease of interest - for example, motor neurons for amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy (SMA) - and to those most commonly affected by drug side effects (cardiac myocytes and hepatocytes).

To address possible mechanism(s) for these beneficial effects, cardiac-specific transgenic mice expressing HSPB8 were generated.

These decreases are of sufficient magnitude to effect cardiac function.

Most tricyclics have a sedating effect, cardiac toxicity, and varying degrees of anticholinergic side effects, which some individuals, especially the elderly, have difficulty tolerating.

We show that wild populations of D. melanogaster indeed carry major-effect cardiac failure-promoting alleles, and that these can be mapped by standard linkage methods.

Possible mechanisms could be a reduction of edema in the heart or electrolyte shifts that effect cardiac function.