Sentence examples for effects can be administered from inspiring English sources
An underlying principle of anti-cancer combination chemotherapy is that drugs, that function through separate cytotoxic mechanisms and have different dose-limiting adverse effects, can be administered together at full doses, with a resulting superior outcome [ 1, 2, 6].
Low-risk therapies with minimal side effects can be administered ethically before clinical onset (in primary prevention trials), but they require a large number of screened subjects in order to identify a reasonable number of eligible participants, are very expensive and may take a long period of time to document results.
The main disadvantage of alpha-lipoic acid is that it needs to be administered intravenously for the first 3 weeks to achieve the desired effect, whereas rosuvastatin can be administered orally once a day.
For the definition of multidrug resistance we considered antimicrobial agents which have a bactericidal effect on P. aeruginosa and can be administered as effective monotherapy.
In contrast, Rhodamine dye-loaded polymersomes, applied at the concentration tested in this work (0.005 mM), have no detrimental effect on cell viability and can be administered as multi-doses.
IFN-α-free regimens that are effective against all HCV genotypes and that can be administered orally with minimal side effects appear within reach.
Currently available treatments have anti-tumor efficacy but they also produce undesirable side effects to normal tissue, limiting the treatment that can be administered.
Though warfarin can be administered orally, its unpredictable anticoagulant effect means that it must be regularly monitored.
In extreme situations, flumazenil can be administered to inhibit or reverse the effects of midazolam.
Phase I trials demonstrate that endostatin, an endothelial cell toxin, can be administered safely, but no obvious anti-tumor effects were observed.
However, when intercalated within a lipid membrane, the hydrophobic drug can be administered to a patient with minimal toxic effects.
