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Exact(19)
Due to its high reactivity, FA leads primarily to local genotoxic effects at the site of contact.
These cells can potentially be mobilized into the circulation in response to injury signals and exert their reparative effects at the site of injury.
We find strong evidence for long-term human-induced edge effects at the site that is closest to the border of the protected area (Treetops); this site registered the strongest losses in total wildlife population numbers, aggregate wildlife biomass, and species richness.
This suggests that chromatin effects at the site of integration rather than copy number accounts for the difference in transgene expression between the two strains.
This was unexpected given that the prion promoter drives higher expression in neurons, and suggests that transgene expression may have been influenced by effects at the site of integration.
Higher dose levels of 20 or 25 mg/kg/day could not be used due to manifestation of overt toxicity and serious inflammatory effects at the site of injection.
Similar(41)
Fire effects at the site-level were more influential than landscape context effects arising from heterogeneity in the fire regime (e.g. extent of surrounding unburnt forest).
Analyzing adaptive functions of fixed differences relies on genotype phenotype correlations involving natural mutational variation, or experimental, effects at the sites or gene of interest.
There were 575 reports relating to side-effects at the site of the injection, such as swelling and extreme pain, and another 241 allergic reactions, such as rash, swollen face and swollen lips.
It is still unclear how each cell subset either individual or together, shows their effect at the site.
Vaccines are usually efficacious only with a certain degree of tissue injury induced by the irritating effect at the site of injection of the adjuvant.
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