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However, according to Zhao et al. (2010), this result implies a typical competitive mediation effect where the directions of direct and indirect effects are opposite.
Dex and 25-OH effects are opposite (25-OH activates sPLA2-IIA promoter while Dex represses it).
Although the risk alleles for the associations of both the ZNF224 and PCK1 loci with the intermediate phenotypes in our cohort also increase risk of AD diagnosis (Table 3), their effects are opposite to that reported in the original GWA studies [6], [10].
However, these effects are opposite to those of locomotion, which reduces spatial competition.
Many of the Mas-R effects are opposite to those of AT1-R.
These effects are opposite to those derived from alterations in PP2A phosphatase.
Similar(50)
At the reach scale, LW addition enhanced the biomass of invertebrates and shredders in summer but the effects were opposite in winter.
However, the direction of effects was opposite to that observed in the European descent samples [7], [21].
We therefore conclude that although sensorimotor response and gating are obviously influenced by Fmr1-KO in both humans and mice, the direction of the effects is opposite.
The B6 background was also more sensitive to the effects of the Fmr1 mutation on PPI, but the direction of these effects was opposite to expectation: Fmr1-KOs displayed enhanced PPI.
However, reaction times were affected by fairness only for the low offers, and the effects were opposite to what was expected, with faster responses for less fair offers.
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