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One possible explanation for the molecular and physiological phenotype of atx-3 nulls is that the absence of ataxin-3 at some timepoint of the development causes cellular (proteotoxic?) stress, which activates the stress machinery, and once they are needed again, chaperones and other effectors will be more effectively and rapidly activated- a process known as hormesis.
Upon endothelial apoptosis, pro-inflammatory effectors will be secreted for the recruitment of leucocytes recruitment to injured sites.
Several more gain and loss of function studies and colocalization (or otherwise) of effectors will be needed before any conclusion is reached.
As additional races and divergent isolates are re-sequenced, polymorphic effectors will be more easily distinguished from underlying genetic diversity between isolates, streamlining the cataloging of potential avirulence/virulence proteins for testing.
Thus, identifying Rab17-specific effectors will be one of the most important tasks in future Rab17 research designed to understand the molecular mechanism by which Rabex-5 determines the targeting of its downstream Rab proteins to neurites at the cellular level.
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In these analyses, the existence of lateralized ERP components sensitive to the cued movement direction will be reflected by hemisphere × cued direction interactions, while lateralized effects sensitive to the cued effector will be indicated by hemisphere × cued effector interactions.
The sight of an effector such as a hand will activate motor representations for many hand actions, and thus, the motor representation(s) activated by the sight of the effector will be less specific than that activated by the sight of a finger movement.
To gain a better understanding of Phytophthora pathogenicity, and the variation in this trait due to endogenous gene silencing of effectors, it will be crucial to experimentally determine which effectors are essential or functionally redundant.
Even though robots can be operated in end effector mode and joint mode, for motion sensing commanding, end effector mode will be more compatible regardless of different DOFs configuration.
That will mean that while Baxter comes with a simple hand, or "end effector," it will be able to adapt the system with more complex and capable hands that will be able to perform tasks that require greater dexterity.
Age-associated modulation of these effector systems will be discussed in the context of the immune deficiency of T-cells.
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