Sentence examples for effectors that have from inspiring English sources
Taken together, the biological outcomes of histone marks are impacted by both their location in chromatin regions and the repertoire of effectors that have access to those regions.
Investigations are in progress to study the Sirt-1 interaction also with small allosteric effectors that have been recently identified [19].
ELISA assays were performed to investigate whether the neuroprotective action of resveratrol involved a modulation of the activity of caspases and p38 MAPK, two intracellular effectors that have been reported to be involved in the apoptotic effect of NO production (30).
Here we focus on selected intermediaries and effectors that have an identifiable role in microalbuminuria.
Additionally, we carefully analyzed the molecular effectors that have been believed to be closely associated with Toxoplasma virulence and its interactions between parasites and host cells.
Effectors that have been characterized to bind to the IRS proteins include PI3K, Grb-2, SHP-2, Fyn, c-Crk, CrkII and Nck [ 9, 27- 32].
The list also included effectors that had previously been identified from G. pallida [ 59, 60].
BteA is a 68 kDa cytotoxic effector that has been identified in B. bronchiseptica but not in the B. pertussis human pathogen.
BteA is the only cytotoxic effector that has been identified in Bordetella spp. In B. pertussis, low-passage clinical strains have an ability to express a functionally active T3SS; however, BteA protein had not been detected in the clinical and common laboratory-adapted strains by MALDI-TOF mass spectrometry [22].
BteA is the only Bordetella effector that has been identified and its central importance is illustrated by the observation that null mutations in bteA recapitulate phenotypes associated with mutations that eliminate type III secretion altogether (Panina et al., 2005).
Located within this 3p21.3 locus, the RAS-association domain family 1, isoform A gene (RASSF1A) encodes a RAS effector that has been identified as a tumour suppressor of many different cancer types (Dammann et al, 2000).
