Sentence examples for effectors of gene from inspiring English sources
These dsRNAs are processed by Dicer to produce 21 23 nucleotide duplex small interfering RNAs (siRNA) with 2 nucleotide 3' OH overhangs that act as the effectors of gene silencing [2].
The observed bistable long-range and localized pattern formation are critical effectors of gene expression regulation.
Additionally, a number of the metabolites are well known effectors of gene expression and some, such as sucrose, isoleucine and glutamine, have high regulatory potential as determined by correlation analysis [ 28].
Many active genes can dynamically co-localise to shared sites of ongoing transcription, which may be induced by the classical effectors of gene expression including trans-acting factors, enhancers, chromatin modifications, and chromosomal interaction [ 27].
Hence, a great number of mutations fall into the flanking regions of the coding sequences [ 37] and Alu elements become effectors of gene transcription by providing new enhancers, promoters and polyadenylation signals to many genes [ 38].
Perturbations of this type are aimed directly at the ultimate effector of gene regulation.
The dual function of miRs as active effector of gene expression on one hand and as stable biomarker on the other hand opens up fascinating opportunities to improve the understanding and diagnosis of cardiovascular diseases.
That urate may function as an effector of gene activity has also been reported, and a subset of MarR family proteins have been identified that bind urate as their ligand.
Argonaute-bound small RNAs, derived from RNA interference and related pathways, are well-known effectors of posttranscriptional gene silencing (PTGS).
Applying Mosaic-seq to 71 constituent enhancers from 15 super-enhancers, our analysis of 51,448 sgRNA-induced transcriptomes finds that only a small number of constituents are major effectors of target gene expression.
MicroRNAs (miRNA) are now recognized as fundamental effectors of posttranscriptional gene expression control.
