Sentence examples for effector compound from inspiring English sources

The technologies to be discussed include solvent detergent and methylene blue treatments designed to inactivate plasma components and derivatives; psoralens (S-59 amotosalen) S-59 amotosalenhogen-redesignedto of platelets; and two products aimed at red blood cells, S-303 (a Frale—frangible anchor-linker effector compounitsand Inactine (a binary ethyleneimine).

As a new hypothesis for effector mediated control on this type of proteins, we propose a model for activation in which the effector compound would pass through a surface crevice instead of binding to a pocket and subsequently being released from the same pocket.

As noted in the literature, the secretion system facilitates transport, injection, and release of effector compounds including enzymes, and toxins in bacteria [ 56, 57 ].

It regulates the expression of the divergently transcribed dmp operons, which are involved in phenol degradation, from the Po promoter in response to aromatic effector compounds (e.g., phenol and cresol) [ 20].

Baell and Holloway [17] have identified a set of chemical substructures that are frequently observed as effectors in compound screening and thus deemed to be promiscuous.

The genomic locations of the gene clusters encoding anti-macrophage effectors and compounds are worthy of brief discussion before a detailed discussion of the clusters themselves and their potential role in infection biology.

We therefore sought to identify novel allosteric effectors from a compound library with diverse chemical scaffolds.

Enzyme activity is often modulated by an allosteric effector, a small natural compound that binds to the enzyme at a site distinct from the substrate-binding site.

At present, only a limited number of effector molecules and tool compounds are known to modulate EMV release or fusion, 207– 209, 355 among them the antidiabetic sulfonylurea drug, glimepiride.

Identifying the downstream effectors of SINE compound-mediated neuroprotection is an important next step towards the goal of developing more potent agents with a wider therapeutic index.

Several successful macrophage-based screens were focused on identifying compounds that increase control of intracellular bacteria in vitro with the idea to use those compounds to boost effector immunity in vivo3,5.