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A future challenge will be to elucidate the function of the U. maydis effector battery, which is likely to consist not only of conventionally secreted proteins but also of proteins secreted by unconventional routes (Reissmann S. and Kahmann R., unpublished) and to elucidate their mode of uptake by host cells.
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Evo-devo studies established that because of optimal pleiotropy, the gain or loss of a trait will likely proceed by the co-option of a local regulator that responds to global cues and controls a battery of effector genes, rather than a major upstream regulator or multiple downstream effectors [ 10 13].
Although the immune system possesses a battery of effector mechanisms designed to rid the body of neoplasms, tumors are capable of rapidly evolving and countering even the most sophisticated immunological effector mechanisms.
During plant tissue invasion M. oryzae secretes a battery of effector proteins to counteract plant defense responses and manipulate the host and facilitate fungal growth.
Differential selection for a battery of effectors that are not recognized by the host could be the basis of host specialization of B. graminis [41].
The related wheat pathogen Pyrenophora tritici-repentis also produces a battery of effectors.
The presence of large batteries of secreted effector proteins, encoded by gene specifically expressed during host invasion is, however, in marked contrast to the human pathogens studied here.
Apart from putative effectors, members of the secretome had homology to a battery of glycoside hydrolases and subtilisin-like serine proteases that likely contribute to the penetration of the plant cuticle and cell wall [ 47].
Salmonella spp. utilize a specialized protein secretion system to deliver a battery of effector proteins into host cells.
-End effector: What specific tasks will the robot perform?
Battery life.
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