Despite the widespread use of opioids to control pain, their clinical effectiveness is hampered by adverse side effects that result mainly from activation of receptors in the central nervous system (CNS).
But its effectiveness is hampered by a banking system that, despite passing the ECB's asset-quality review and the latest stress tests, remains fragile.To maximise impact, the ECB should offer to buy whole portfolios of SME loans (and possibly other kinds of loans) off bank balance sheets at just below par and cut the interest rate on these loans substantially.
Chemotherapy is still the treatment of choice for many types of cancer; but its effectiveness is hampered by dose limiting toxicity.
Current research in the field of childhood weight management (WM) effectiveness is hampered by inconsistent terminology and criterion for WM programme completion, alongside other engagement-related concepts (e.g. adherence, dropout and attrition).
Screening colonoscopy effectiveness is hampered by limited adherence by the general population.
DOI: http://dx.doi.org/10.7554/eLife.00090.002 Doxorubicin (Adriamycin) is used widely to treat diverse types of cancer, yet its effectiveness is hampered by the existence of drug-resistant cancer cells.
It is known to be efficacious, but effectiveness is hampered by dysfunctional systems for supply and distribution (particularly at community level), low utilization of antenatal care (ANC), a lack of community demand for IFA requiring promotion and counseling, and barriers to access (5, 13, 29).
The therapeutic effectiveness of photodynamic therapy (PDT) was hampered by the poor water solubility and instability in physiological conditions of the photosensitizers.
There were indications that the potential effectiveness of self-assessment and feedback was hampered by limitations in the teaching environment.
According to this study, the effectiveness of the Rwanda CHW system was hampered by an irregular system of supervision and trainings.
