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The effectiveness of this compound is due to chelation of metal ions through imidazol, imino and pyridine nitrogen donors.
Moreover, the effectiveness of this compound is also supported by the observation that chemotherapy with [Pt(O,O'-acac)(γ-acac)(DMS)] was well tolerated.
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Compounding these limitations, L-DOPA therapy tends to lose effectiveness over time, L-DOPA-induced dyskinesias are a common complication of chronic dopaminergic therapy, and metabolites of this compound are neurotoxic [1].
This compound is experimentally useful in that it blocks both mouse and human VEGFR2, thus allowing us to demonstrate the effectiveness of this drug in a fully immunocompetent mouse model.
However, the effectiveness of these compounds is still under evaluation (Hartline et al., 2005; Paolino et al., 2011).
Effectiveness of these compounds was assessed through potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) measurements.
The effectiveness of those compounds was elucidated by both the experimental data and molecular docking simulations.
However, the in vivo effectiveness of this compound has been questioned.
In this work, a simple nonlinear time-dose tool to test the effectiveness of antioxidant compounds is presented.
Due to favorable extraskeletal effects and based on current data on fracture prevention, the cost-effectiveness of this compound could be improved compared with other antiresorptive agents.
The effectiveness of this new design is still being tested.
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