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The effectiveness measures for the cost-effectiveness analysis will be obtained directly from the primary statistical analysis.
Intervention cost and effectiveness measures for the prevention of chronic diseases were unavailable in the Portuguese literature.
Effectiveness measures for dichotomous outcomes will be benefit and risk ratios (depending on the beneficial/adverse character of the outcome).
Because cost and effectiveness data were unavailable for diabetes screening, we used the available cost and effectiveness measures for cholesterol screening as proxy.
Effectiveness measures for patients with PsA included the modified Psoriatic Arthritis Response Criteria (mPsARC) [ 26]; ≥ 50% improvement in the American College of Rheumatology response criteria (ACR50) [ 27]; TJC (0 to 78 joints), SJC (0 to 76 joints), and changes in TJC and SJC; and the Health Assessment Questionnaire Disability Index (HAQ DI, 0 to 3) [ 28].
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An effectiveness measure for fuzzy rules is developed that allows for systematic addition or deletion of rules during the GA optimization process.
All EQ-5D calculations allow a comprehensive evaluation of the actual value of an intervention for the patient: it is a comparative effectiveness measure for HRQoL that is recognized as reliable, valid, and responsive in the literature [ 37, 38].
The unit of health of interest and the effectiveness measure for this study was the proportion of children with diarrhea ≤ 4 days, since mortality is an infrequent outcome and would require a large sample size.
Collected characteristics were the author(s) and year of publication, the study topic, a short description of the intervention, the effectiveness measure for CEA, the cognitive (intermediate) outcome measures of behavior change, the type of behavioral model used and a short description of the application of the cognitive outcome measure in the study (Table 1).
Table 3 shows the 95%% credible interval for the five cost-effectiveness measures for each of the four interventions.
We used standardized cost-effectiveness measures for modeling T2D disease interventions, which allow comparison with other published findings and HRQoL of other diseases [ 38].
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