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Evaluating their effectiveness is tricky.
Effectiveness is often smaller than efficacy.
What evidence of their effectiveness is there?
This loss in effectiveness is called tolerance.
"Cost effectiveness is only a factor".
But effectiveness is not the point.
But their effectiveness is already diminishing.
Effectiveness is important but not enough.
"In reality, the cost effectiveness is insufficient to warrant it.
They can be intimidating and their effectiveness is questionable.
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Cost-effectiveness is another consideration.
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