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We extracted from the literature the proportion of participants who held negative views about how generics were perceived compared to their branded equivalent for the following five perceptions: drug effectiveness, drug quality, the likelihood of causing side effects, drug safety and attitude towards generic substitution or the process of replacing a branded medication with its generic equivalent.
7 Factors that reportedly influence their price setting include research and development (R & D) costs, clinical effectiveness, drug quality and disease prevalence.
There were five attributes with scores higher than the average (0.1), and the ranked order of the first three was clinical efficacy and effectiveness, drug safety, and bioequivalence.
When the decision is based on cost effectiveness, Drug C is chosen over Drug D in spite of the higher direct cost of Drug C, because Drug C is more cost effective.
ICER = (Cost drug − Cost absence of treatment ) (Effectiveness drug − Effectiveness absence of treatment ) The analysis conducted is a cost utility analysis, ie, an economic evaluation that estimates the cost per quality-adjusted life-year (QALY) gained from undertaking one intervention instead of another.
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Today, research evidence is generally constrained to a single problem, such as the effectiveness of drug treatment.
Thus, the effectiveness of drug treatment may vary according to ER, p53, and/or HER2 expression.
The main reason of low chemotherapy effectiveness is drug resistance of cancer cells.
Therefore, it is difficult to assess the effectiveness within drug classes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com